After several attempts to reboot the server via web management console it seems to work again. I think I'll trigger a hardware test of the server soon. Maybe tomorrow morning or so.
for now tested from Killogy and me, 2018,2019, 2021, 2022, rest will be test tomorrow, all plugins works in servers, in all difficulties, voting, selfhelp or helping teammate progress normal speed (same cvar) No crash, no spike lags, no long loading